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Since I didn't quite answer your question before, the two hemispheres of the cortex are surprisingly independent. However, there's a big "interconnect" in the middle called the corpus callosum, which is a bundle of axons that cross from one hemisphere to another. It's fairly easy to find on an MRI--it's the elongated u-shaped object with the labels on it here: https://en.wikipedia.org/wiki/Corpus_callosum#/media/File:Co... (The labels indicate different parts of it).

For patients with really severe epilepsy (where the seizueres are causing slips and falls), one possible treatment is to cut this bundle to prevent the epileptic activity from spreading across both hemispheres. You basically just slice through them with a knife. Since neurons are very small and delicate, it's extremely unlikely that the membranes (essentially drops of oil) would reform in a way that would permit them to carry information.

Since the corpus callosum contains most of the inter-hemispheric connections, cutting it is often sufficient to prevent the siezure from spreading (and also to produce weird split-brain phenomena). However, there are a few other locations where there are cross-hemispheric connections. The anterior and posterior commissure are two other "interconnects." There may also some much more indirect interactions through subcortical structures.




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